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Although the opiate receptor relies on G protein coupling for signal transduction, this receptor was identified to utilize arrestin activation for internalization of the receptor. Otherwise, the receptor promoted no other signaling cascades (fifty nine) Modifications of conolidine have resulted in variable improvement in binding efficacy. This bind
**It is a subjective assessment based upon the toughness with the offered informations and our estimation of efficacy.When the opiate receptor depends on G protein coupling for sign transduction, this receptor was identified to utilize arrestin activation for internalization on the receptor. Otherwise, the receptor promoted no other signaling casca
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